Plasma Collection From Convalescent and/or Immunized Donors for the Treatment of COVID-19
Clara Health

Plasma Collection From Convalescent and/or Immunized Donors for the Treatment of COVID-19

Sponsored by National Institutes of Health Clinical Center (CC)


The Coronavirus disease 2019 (COVID-19) pandemic is a major public health issue. Right now, there is no vaccine to keep people from getting sick. There is also no treatment for people who do get sick. Researchers want to collect plasma from people who have recovered from COVID-19. The plasma will have antibodies against the virus that causes COVID-19.

If a vaccine is made, people who develop immunity from the vaccine can also donate plasma.

About 
COVID-19

Coronavirus disease 2019 (COVID-19) is a respiratory illness that can spread from person to person. The virus that causes COVID-19 is a novel coronavirus that was first identified during an investigation into an outbreak in Wuhan, China.

How is this study designed?

Objective: To collect plasma from people who have recovered from COVID-19 or have been vaccinated against the coronavirus that causes COVID-19, so that the plasma can be used to treat people with the disease.

Study type: Observational Estimated Enrollment: 1500 participants Actual Study Start Date: April 21, 2020 Estimated Study Completion Date: April 14, 2030

Who is this study for?

Study Population Community donors who have recovered from COVID-19, or have been immunized against SARS-CoV-2.

What should I expect?

  • Participants will be screened with a physical exam, medical history, and blood sample. Their pulse, blood pressure, and temperature will be taken. Their height and weight will be recorded.
  • Participants will donate plasma. It will be collected through whole blood donation or through apheresis.
  • For whole blood donation, a needle will be placed in the participant's arm vein. Blood will be withdrawn.
  • For apheresis, a needle will be placed in the participant's arm vein. Blood will be withdrawn. A machine will separate the plasma from the red cells. The plasma will be removed, and the rest of the cells will be returned to the participant either through the same needle or through a needle in their other arm.
  • Participants will have 3 to 20 plasma donations.
  • Participation will last up to 240 days.

Connect with the study team

Thank you for your interest in advancing COVID-19 treatments.

Please fill out this contact form to be connected to a member of the study team. The following information that you enter will only be authorized to be shared with the research team conducting this specific study.

If you have any difficulties or questions, please contact our support specialists at [email protected]

Have a question?

For general questions about COVID-19 clinical trials, please email [email protected] For study specific inquiries, submit the interest form and you’ll be connected to the study team.