Pandemic Response Network
Clara Health

Pandemic Response Network

Sponsored by Duke University

Coronavirus Disease 19 (COVID-19) represents an unprecedented challenge to the operations and population health management efforts of health care systems around the world.

The "Pandemic Research Network (PRN): Duke Community Health Watch" study leverages technology, clinical research, epidemiology, telemedicine, and population health management capabilities to understand how to safely COVID-19.


Coronavirus disease 2019 (COVID-19) is a respiratory illness that can spread from person to person. The virus that causes COVID-19 is a novel coronavirus that was first identified during an investigation into an outbreak in Wuhan, China.

How is this study designed?

Study Type: Observational Estimated Enrollment: 20000 participants Actual Study Start Date: April 3, 2020 Estimated Study Completion Date: December 31, 2021

Who is this study for?

The target population is individuals in the Duke Health region as well as individuals beyond the Duke Health region who have flu-like symptoms, a viral test order for COVID-19, confirmed COVID-19, or concern for exposure to COVID-19. A subgroup of particular interest within the target population is health care workers (HCW) and families of HCW.

Inclusion Criteria:

  • flu-like symptoms
  • a viral test order for COVID-19
  • confirmed COVID-19
  • concern for exposure to COVID-19

Exclusion Criteria:

  • None

What should I expect?

  • Community members will enroll in the study electronically and for 28 days will be reminded via email or SMS to submit signs and symptoms related to COVID-19.
  • Participants who report symptoms will be provided information about COVID-19 testing (if needed) and established mechanisms to seek care within Duke Health.
  • Instructions for telemedicine and in-person visits, which is available publicly at, will be presented to participants.
  • Participants who are unable to report symptoms independently may be contacted via telephone by Population Health Management Office (PHMO) or Clinical Events Classification (CEC) team members.

Have questions or need help?

For general questions about COVID-19 clinical trials, please email [email protected] For study specific inquiries, submit the interest form and you'll be connected to the team.