COVID-19 Plasma Collection
Clara Health

COVID-19 Plasma Collection

Sponsored by Thomas Jefferson University


Patients who are severely ill with COVID-19 may benefit from receiving plasma infusions from donors who have recovered from the disease and are proven to no longer be infected. Efforts to initiate the collection and infusion of these products to high risk patients have been initiated around the world and the FDA has recently provided information about how this could be accomplished.

As the Jefferson Blood Donor Center already has processes to collect, test and process blood, we are planning to make efforts to collect plasma for this use should it be necessary.

About 
COVID-19

Coronavirus disease 2019 (COVID-19) is a respiratory illness that can spread from person to person. The virus that causes COVID-19 is a novel coronavirus that was first identified during an investigation into an outbreak in Wuhan, China.

How is this study designed?

Study Type: Interventional (Clinical Trial) Estimated Enrollment: 510 participants Primary Purpose: Treatment Official Title: Outcomes Related to COVID-19 Treated With Hydroxychloroquine Among In-patients With Symptomatic Disease (ORCHID) Actual Study Start Date: April 2, 2020 Estimated Study Completion Date: July 2021

Who is this study for?

Inclusion Criteria*:

  • Age 18 years and older
  • Prior diagnosis of COVID-19 documented by a laboratory test approved by the FDA
  • Either: Complete resolution of all COVID-related symptoms for 14-28 days at the time of blood donation AND negative repeated SARS-CoV-2 test OR Complete resolution of all COVID-related symptoms for > 28 days

Exclusion Criteria*:

  • Failure to pass standard volunteer blood donor screening criteria required by the Jefferson Blood Donor Center and the FDA
  • Currently pregnant

* Additional criteria apply. Please speak with the study team for further information.

What should I expect?

The purpose of this study is to describe the process for identifying and collecting convalescent plasma from donors previously infected with the virus. The research portion on top of this standard blood product collection will the process of identification of subjects and processes by which blood products are processed in this special population.

This protocol does not involve the administration of blood products to patients with COVID-19 infection.

Have questions or need help?

For general questions about COVID-19 clinical trials, please email [email protected] For study specific inquiries, submit the interest form and you'll be connected to the team.